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Design Automation Methods and Tools for Microfluidics-Based Biochips

โœ Scribed by Fei Su, Krishnendu Chakrabarty (auth.), Krishnendu Chakrabarty, Jun Zeng (eds.)


Publisher
Springer Netherlands
Year
2006
Tongue
English
Leaves
405
Edition
1
Category
Library

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โœฆ Synopsis


Microfluidics-based biochips, also known as lab-on-a-chip or bio-MEMS, are becoming increasingly popular for DNA analysis, clinical diagnostics, and the detection/manipulation of bio-molecules. As the use of microfluidics-based biochips increases, their complexity is expected to become significant due to the need for multiple and concurrent assays on the chip, as well as more sophisticated control mechanisms for resource management. Time-to-market and fault tolerance are also expected to emerge as design considerations. As a result, current full-custom design techniques will not scale well for larger designs. There is a need to deliver the same level of CAD support to the biochip designer that the semiconductor industry now takes for granted.

Design Automation Methods and Tools for Microfluidics-Based Biochips deals with all aspects of design automation for microfluidics-based biochips. Experts have contributed chapters on various aspects of biochip design automation. Topics include device modeling; adaptation of bioassays for on-chip implementations; numerical methods and simulation tools; architectural synthesis, scheduling and binding of assay operations; physical design and module placement; fault modeling and testing; reconfiguration methods.

โœฆ Table of Contents


MICROFLUIDICS-BASED BIOCHIPS: TECHNOLOGY ISSUES, IMPLEMENTATION PLATFORMS, AND DESIGN AUTOMATION CHALLENGES....Pages 1-29
MODELING AND SIMULATION OF ELECTRIFIED DROPLETS AND ITS APPLICATION TO COMPUTER-AIDED DESIGN OF DIGITAL MICROFLUIDICS....Pages 31-52
MODELING, SIMULATION AND OPTIMIZATION OF ELECTROWETTING....Pages 53-84
ALGORITHMS IN FASTSTOKES AND ITS APPLICATION TO MICROMACHINED DEVICE SIMULATION....Pages 85-107
COMPOSABLE BEHAVIORAL MODELS AND SCHEMATIC-BASED SIMULATION OF ELECTROKINETIC LAB-ON-A-CHIP SYSTEMS....Pages 109-142
FFTSVD: A FAST MULTISCALE BOUNDARY ELEMENT METHOD SOLVER SUITABLE FOR BIO-MEMS AND BIOMOLECULE SIMULATION....Pages 143-168
MACROMODEL GENERATION FOR BIOMEMS COMPONENTS USING A STABILIZED BALANCED TRUNCATION PLUS TRAJECTORY PIECEWISE LINEAR APPROACH....Pages 169-187
SYSTEM-LEVEL SIMULATION OF FLOW INDUCED DISPERSION IN LAB-ON-A-CHIP SYSTEMS....Pages 189-214
MICROFLUIDIC INJECTOR MODELS BASED ON ARTIFICIAL NEURAL NETWORKS....Pages 215-233
COMPUTER-AIDED OPTIMIZATION OF DNA ARRAY DESIGN AND MANUFACTURING....Pages 235-269
SYNTHESIS OF MULTIPLEXED BIOFLUIDIC MICROCHIPS....Pages 271-300
MODELING AND CONTROLLING PARALLEL TASKS IN DROPLET-BASED MICROFLUIDIC SYSTEMS....Pages 301-327
PERFORMANCE CHARACTERIZATION OF A RECONFIGURABLE PLANAR ARRAY DIGITAL MICROFLUIDIC SYSTEM....Pages 329-356
A PATTERN-MINING METHOD FOR HIGH-THROUGHPUT LAB-ON-A-CHIP DATA ANALYSIS....Pages 357-400

โœฆ Subjects


Electronics and Microelectronics, Instrumentation;Biomedical Engineering;Circuits and Systems;Biotechnology;Engineering Fluid Dynamics;Biophysics/Biomedical Physics


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