Micro-Electrode-Dot-Array Digital Microfluidic Biochips: Design Automation, Optimization, and Test Techniques

✍ Scribed by Zipeng Li, Krishnendu Chakrabarty, Tsung-Yi Ho, Chen-Yi Lee

• Publisher: Springer International Publishing
• Year: 2019
• Tongue: English
• Leaves: 152
• Edition: 1st ed.
• Category: Library

✦ Synopsis

This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.

✦ Table of Contents

Front Matter ....Pages i-xiii
Introduction (Zipeng Li, Krishnendu Chakrabarty, Tsung-Yi Ho, Chen-Yi Lee)....Pages 1-20
Droplet Size-Aware High-Level Synthesis (Zipeng Li, Krishnendu Chakrabarty, Tsung-Yi Ho, Chen-Yi Lee)....Pages 21-51
Efficient and Adaptive Error Recovery (Zipeng Li, Krishnendu Chakrabarty, Tsung-Yi Ho, Chen-Yi Lee)....Pages 53-81
Fault Modeling, Structural Testing, and Functional Testing (Zipeng Li, Krishnendu Chakrabarty, Tsung-Yi Ho, Chen-Yi Lee)....Pages 83-112
Generalized Error-Correcting Sample Preparation (Zipeng Li, Krishnendu Chakrabarty, Tsung-Yi Ho, Chen-Yi Lee)....Pages 113-134
Conclusions and New Directions (Zipeng Li, Krishnendu Chakrabarty, Tsung-Yi Ho, Chen-Yi Lee)....Pages 135-141
Back Matter ....Pages 143-144

✦ Subjects

Engineering; Circuits and Systems; Biomedical Engineering; Processor Architectures