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Depletion of CD4+ CD25+ regulatory T cells inhibits local tumour growth in a mouse model of B cell lymphoma

✍ Scribed by I. Heier; P. O. Hofgaard; P. Brandtzæg; F. L. Jahnsen; M. Karlsson


Book ID
108699817
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
320 KB
Volume
152
Category
Article
ISSN
0009-9104

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In mouse liver transplantation, tolerance is readily inducible. Recent studies have revealed that CD25+ CD4+ regulatory T cells play an important role in regulating various immune responses, including transplant tolerance. However, the contribution of these cells to tolerance in mouse liver transpla