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Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia

✍ Scribed by Kleppe, Maria; Lahortiga, Idoya; El Chaar, Tiama; De Keersmaecker, Kim; Mentens, Nicole; Graux, Carlos; Van Roosbroeck, Katrien; Ferrando, Adolfo A; Langerak, Anton W; Meijerink, Jules P P


Book ID
109914609
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
760 KB
Volume
42
Category
Article
ISSN
1061-4036

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## Abstract Gene amplification is a relatively rare event in hematologic malignancies. The __ABL__ gene on chromosome band 9q34 is a proto‐oncogene and is the well‐known translocation partner of the __BCR__ gene on 22q11 giving rise to t(9;22)(q34;q11), which is the hallmark of chronic myeloid leuk