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Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia

✍ Scribed by Goodman, Patricia A; Burkhardt, Nicole; Juran, Brian; Tibbles, Heather E; Uckun, Faith M


Book ID
110067428
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
310 KB
Volume
22
Category
Article
ISSN
0950-9232

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## Abstract Acute lymphoblastic leukemia (ALL) is a heterogeneous disorder, with the greatest prevalence in children, but it also affects adults, and has an increasing incidence with age. Chromosomal abnormalities in ALL have been frequently described, the most common is the Philadelphia chromosome