Dehydrative metabolites of 1-(3-chlorophenyl)-1-methyl-2-phenyl-2-(2-pyridine)ethanol as potential hypocholesteremic agents
✍ Scribed by Kokosa, J. M.; Sinsheimer, J. E.; Wade, D. R.; Drach, J. C.; Burckhalter, J. H.
- Book ID
- 127315506
- Publisher
- American Chemical Society
- Year
- 1978
- Tongue
- English
- Weight
- 566 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract 2‐(2‐Pyridine)‐1‐(3‐chlorophenyl)‐2‐phenyl‐1‐methylethanol (I), containing tritium uniformly distributed in the 2‐phenyl ring, was synthesized in two steps with tritiated benzene as the labelled starting material. An improved procedure was employed for the coupling of m‐chloroacetophen
The title compound, C 24 H 17 N 4 Cl, was synthesized by the reaction of 5-amino-3-methyl-1-phenylpyrazole with 3-(2chlorophenyl)-1-(2-pyridyl)prop-2-en-1-one in glycol under microwave irradition. X-ray crystal structure analysis reveals that the substituted pyridine ring is almost coplanar with the