Nijmegen breakage syndrome: consequences
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Martin Digweed; AndrΓ© Reis; Karl Sperling
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Article
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1999
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John Wiley and Sons
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English
β 85 KB
The autosomal recessive genetic disorder, Nijmegen Breakage Syndrome, is characterised by an excessively high risk for the development of lymphatic tumours and an extreme sensitivity towards ionising radiation. The most likely explanation for these characteristics, a deficiency in the repair of DNA