𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Expression of ATM in ataxia telangiectasia fibroblasts rescues defects in DNA double-strand break repair in nuclear extracts

✍ Scribed by Yuling Li; Michael P. Carty; Gregory G. Oakley; Michael M. Seidman; Mario Medvedovic; Kathleen Dixon

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
172 KB
Volume
37
Category
Article
ISSN
0893-6692

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Joining of correct and incorrect DNA dou
Joining of correct and incorrect DNA double-strand break ends in normal human and ataxia telangiectasia fibroblasts
✍ Markus Löbrich; Martin Kühne; Jana Wetzel; Kai Rothkamm 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB 👁 1 views

Chromosomal aberrations are believed to result from the incorrect joining of DNA double-strand breaks (DSBs). In an attempt to investigate induction and rejoining quality of DSBs following ionizing radiation exposure in specific genomic locations of mammalian DNA, an experimental approach based on S

Rejoining of DNA double-strand breaks in
Rejoining of DNA double-strand breaks in human fibroblasts and its impairment in one ataxia telangiectasia and two fanconi strains
✍ Coquerelle, Thérèse M. ;Weibezahn, Karl F. 📂 Article 📅 1981 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 376 KB

## Abstract Using the technique of neutral elution through polycarbonate filters as a measure of DNA length, and hence of the number of double‐strand breaks incurred as a result of radiation damage, we found that normal human fibroblasts rejoin 50% of all breaks within only 3 min (37°C). This fast

Different types of V(D)J recombination a
Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells
✍ Nicole S. Verkaik; Rebecca E. E. Esveldt-van Lange; Diana van Heemst; Hennie T. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB 👁 1 views

The end-joining pathway of DNA double-strand break (DSB) repair is necessary for proper V(D)J recombination and repair of DSB caused by ionizing radiation. This DNA repair pathway can either use short stretches of (micro)homology near the DNA ends or use no homology at all (direct end-joining). We d