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Defective CD19-dependent signaling in B-1a and B-1b B lymphocyte subpopulations

โœ Scribed by Goutam Sen; Hsin-Jung Wu; Gabriel Bikah; Chandrasekar Venkataraman; Darrell A Robertson; E.Charles Snow; Subbarao Bondada

Book ID
117325441
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
314 KB
Volume
39
Category
Article
ISSN
0161-5890

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## Self-renewal of B-1 lymphocytes is dependent on CD19 The B-l subset of B lymphocytes is maintained by self-renewal of mature cells, and this process may involve signaling through membrane immunoglobulin (mIg). We determined whether CD19, a membrane protein that co-stimulates B cells by mIg, has