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Islet-Infiltrating T Lymphocytes in Insulin-dependent Diabetic Patients Express CD80 (B7-1) and CD86 (B7-2)

✍ Scribed by Akihisa Imagawa; Toshiaki Hanafusa; Naoto Itoh; Jun-ichiro Miyagawa; Hiromu Nakajima; Mitsuyoshi Namba; Masamichi Kuwajima; Shinji Tamura; Sumio Kawata; Yuji Matsuzawa; David M. Harlan


Book ID
115621421
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
784 KB
Volume
9
Category
Article
ISSN
0896-8411

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Costimulation mediated by costimulatory molecules, such as B7-1 and B7-2, which are ligands for the CD28/cytolytic T lymphocyte associated antigen (CTLA)-4 counter-receptor, plays an important role in the induction of T cell-mediated antitumor immunity. We investigated the expressions of B7-1, B7-2,