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Cytogenetic findings in malignant triton tumor

✍ Scribed by Joni A. Travis; Dr. Julia A. Bridge; James R Neff; Avery A. Sandberg

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 502 KB
Volume: 9
Category: Article
ISSN: 1045-2257
DOI: 10.1002/gcc.2870090102

No coin nor oath required. For personal study only.

✦ Synopsis

Malignant triton tumor is a tare histologic variant of malignant schwannoma that shows both n e u d and skeletal muscle differentiation. In this study, cytogenetic analysis of a recurrent malignant triton tumor of the forearm from a 26-year-old female and a primary paraspinal malignant triton tumor from a 27-year-old female revealed complex karyotypes displaying multiple numercial and structural abnormalities. Abnormalities shared by both tumors included three copies of chromosome 22 and structural rearrangements of chromosomes 2, 7, and 21 at identical or closely located breakpoints. Genes Chrom Cancer 9:l-7 (1994).

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