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Cyclin-dependent kinase 5 activators p35 and p39 facilitate formation of functional synapses

✍ Scribed by Jenny U. Johansson; Lena Lilja; Xiao-Liang Chen; Haruhiro Higashida; Björn Meister; Mami Noda; Zhen-Guo Zhong; Shigeru Yokoyama; Per-Olof Berggren; Christina Bark


Book ID
116753358
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
497 KB
Volume
138
Category
Article
ISSN
0169-328X

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The ubiquitously expressed cyclinzone, which may restrict cdk5 activation to the postmidependent kinase 5 (cdk5) is essential for brain develtotic neural cells in the developing brain. The expresopment. Bioactivation of cdk5 in the brain requires sion levels of p35 and p39 mRNAs in the marginal the