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P.1.007 Levels of activators of cyclin-dependent protein kinase 5 (Cdk5) p25 and p35 in Alzheimer's disease

✍ Scribed by O. Engmann; T. Hortobagyi; A. Thompson; K.P. Giese

Book ID
118596674
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
58 KB
Volume
20
Category
Article
ISSN
0924-977X

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## Abstract Cyclin‐dependent kinase 5 (cdk5), in contrast to other members of the cyclin‐dependent kinase family, is not activated by cyclins but instead is activated by complexing with neuron‐specific activator molecules (p35, p39, and p67). The most effective activator of cdk5 both in vitro and i