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Cyclin D1 protein and CCND1 gene expression in colorectal cancer

✍ Scribed by E. Balcerczak; G. Pasz-Walczak; P. Kumor; M. Panczyk; R. Kordek; R. Wierzbicki; M. Mirowski


Book ID
116442484
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
146 KB
Volume
31
Category
Article
ISSN
0748-7983

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## Abstract Cyclin D1 regulates G1 cell cycle progression by controlling the phosphorylation of the retinoblastoma protein. This pathway is frequently deregulated in many malignancies. In neuroblastoma, however, no consistent G1 cell cycle checkpoint aberrations have been found. We examined the pos