✦ LIBER ✦

Cyclin D1 protein expression and gene polymorphism in colorectal cancer

✍ Scribed by Judith A. McKay; Joy J. Douglas; Val G. Ross; Stephanie Curran; Graeme I. Murray; Jim Cassidy

Publisher: John Wiley and Sons
Year: 2000
Tongue: French
Weight: 82 KB
Volume: 88
Category: Article
ISSN: 0020-7136
DOI: 10.1002/1097-0215(20001001)88:1<77::aid-ijc12>3.0.co;2-o

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Expression of cell-cycle regulatory prot

Expression of cell-cycle regulatory proteins cyclin D1, cyclin E, and their inhibitor p21 WAF1/CIP1 in gastric cancer

✍ M�ller, Wolfram; Noguchi, Tsuyoshi; Wirtz, Hans-Christian; Hommel, Gerhard; Gabb 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 344 KB 👁 2 views

The expression and prognostic role of cyclin D1, cyclin E, and p21 (WAF1/CIP1) were immunohistochemically investivated in 413 curatively resected gastric carcinomas. p21 was expressed in 65•4 per cent (n=270), cyclin D1 in 23•7 per cent (n=98), and cyclin E in 13•6 per cent (n=56) of the tumours. Th

Altered expression of cyclin D1 and CDK4

Altered expression of cyclin D1 and CDK4 genes in ovarian carcinomas

✍ Valeria Masciullo; Giovanni Scambia; Maria Marone; Cecilia Giannitelli; Gabriell 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 130 KB 👁 2 views

We analyzed the expression and amplification of cyclin D1 and CDK4 genes in ovarian carcinomas. Northern blot analysis revealed overexpression of cyclin D1 in 12 of 65 (18%) ovarian carcinomas while CDK4 was overexpressed in 7 of 48 cases (14%). None of the tumors showed amplification of any of the

Cyclin D1 and retinoblastoma susceptibil

Cyclin D1 and retinoblastoma susceptibility gene alterations in non-small cell lung cancer

✍ Antonio Marchetti; Claudio Doglioni; Mattia Barbareschi; Fiamma Buttitta; Silvia 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 256 KB 👁 2 views

Among the major regulators of the G 1 restriction point are cyclin D1 and the retinoblastoma gene product (RB). In non-small cell lung cancer (NSCLC), the cyclin D1 gene is amplified/over-expressed in almost 50% of cases, and RB is inactivated in 6-32% of cases. It is of interest to evaluate concurr

The prognostic value of cyclin D1, p53,

The prognostic value of cyclin D1, p53, and MDM2 protein expression in uveal melanoma

✍ Coupland, Sarah E.; Anastassiou, Gerasimos; Stang, Andreas; Schilling, Harald; A 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 215 KB 👁 2 views

Malignant uveal melanoma is the commonest primary intraocular tumour in adults. It metastasizes frequently and 50% of patients die within 10 years of diagnosis. The expression of cyclin D1, p53, and MDM2 in uveal melanoma and their relationship to metastasis-free 5-year survival was determined, in o

Subcellular localisation of cyclin D1 pr

Subcellular localisation of cyclin D1 protein in colorectal tumours is associated with p21WAF1/CIP1 expression and correlates with patient survival

✍ Tracey A. Holland; Jackie Elder; Jonathan M. McCloud; Christine Hall; Mark Deaki 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 423 KB 👁 2 views

GM-CSF gene expression and protein produ

GM-CSF gene expression and protein production in human colorectal cancer cell lines and clinical tumor specimens

✍ Markus Trutmann; Luigi Terracciano; Christoph Noppen; Judith Kloth; Marlies Kasp 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 471 KB 👁 2 views

Granulocyte-macrophage colony stimulating factor (GM-CSF) gene expression and protein production were investigated in colorectal cancer cell lines and surgical specimens. In 6 of 6 established tumor lines, expression of the GM-CSF gene was observed by reverse transcription polymerase chain reaction