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Crystallization and hydration pressure or formation pressure of solid phases

✍ Scribed by Frank Schmidt-Döhl; Ferdinand S. Rostásy

Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
164 KB
Volume
25
Category
Article
ISSN
0008-8846

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Liquid–liquid miscibility gaps and hydrate formation in drug–water binary systems: Pressure–temperature phase diagram of lidocaine and pressure–temperature–composition phase diagram of the lidocaine–water system
✍ René Ceolin; Maria Barrio; Josep-Lluis Tamarit; Nestor Veglio; Marc-Antoine Perr 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 388 KB 👁 1 views

The pressure-temperature (P-T) melting curve of lidocaine was determined (dP/dT = 3.56 MPa K(-1)), and the lidocaine-water system was investigated as a function of temperature and pressure. The lidocaine-water system exhibits a monotectic equilibrium at 321 K (ordinary pressure) whose temperature in