✦ LIBER ✦

Cross-clade T cell recognition of HIV.1

✍ Scribed by Frances Gotch

Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 647 KB
Volume: 10
Category: Article
ISSN: 0952-7915
DOI: 10.1016/s0952-7915(98)80109-x

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✦ Synopsis

Despite considerable advances in antiviral therapy for HIV infection, successful global intervention will require an effective vaccine. Current evidence suggests that cytotoxic T lymphocyte responses will be an important component of such vaccination. Recent evidence suggests that cytotoxic T lymphocytes raised against viral antigens from different clades (subtypes) of HIV.1 can cross-react extensively and such data have major implications for HIV vaccine design.

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