✦ LIBER ✦

HIV-2 and T cell recognition

✍ Scribed by Hilton C Whittle; Koya Ariyoshi; Sarah Rowland-Jones

Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 823 KB
Volume: 10
Category: Article
ISSN: 0952-7915
DOI: 10.1016/s0952-7915(98)80108-8

No coin nor oath required. For personal study only.

✦ Synopsis

HIV-2 is less pathogenic and less transmissible than HIV-1. Recent research in relation to deletions in the HIV nef gene and to immune cross-reactions between infections by HIV-2, HIV-1 and simian immunodeficiency virus suggests that T cell recognition and the control of viral replication may be more efficient in HIV-2 infection than in HIV-1 infection. These insights may be crucial to the design of effective vaccines.

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