HIV and idiotypic T-cell regulation
β Scribed by Michael Grant
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 210 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0167-5699
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Homeostatic regulation of cell numbers is an important principle in biology. Mechanisms that function to maintain or re-establish homeostasis in the immune system include interactions among antigen-presenting cells, regulatory T cells and cytokines. The vital role that homeostatic regulation plays i
HIV-2 is less pathogenic and less transmissible than HIV-1. Recent research in relation to deletions in the HIV nef gene and to immune cross-reactions between infections by HIV-2, HIV-1 and simian immunodeficiency virus suggests that T cell recognition and the control of viral replication may be mor
## Abstract Allotypic restriction of idiotype suppression has been shown in several idiotypic systems. It has also been demonstrated that naive BALB/c mice contain naturally occurring suppressor T cells capable of inhibiting the Mβ460 idiotype expressed on BALB/c B cells, and that T cells from allo