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Cross-sensitization to haptens: formation of common haptenic metabolites, T cell recognition of cryptic peptides, and true T cell cross-reactivity

✍ Scribed by Marty Wulferink; Sabine Dierkes; Ernst Gleichmann


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
180 KB
Volume
32
Category
Article
ISSN
0014-2980

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## Abstract The human major histocompatibility complex class I antigen HLA‐B\*2705 binds several sequence‐related peptides (pVIPR, RRKWRRWHL; pLPM2, RRRWRRLTV; pGR, RRRWHRWRL). Cross‐reactivity of cytotoxic T cells (CTL) against these HLA‐B\*2705:peptide complexes seemed to depend on a particular p