๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

T-cell recognition of influenza-infected cells

โœ Scribed by Brigitte A. Askonas


Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
107 KB
Volume
2
Category
Article
ISSN
0167-5699

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Anti-viral cytotoxic T cells (Tc) recognize virus only in conjunction with class I MHC molecules in man and mouse (Zinkernagel and Doherty 1979). Antibodies directed to the target cell H-2 molecule inhibit T-cell-mediated cytotoxicity, while no inhibition is observed when anti-H-2 binds to the Tc an

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A series of 16 H-2b-restricted, A influenza virus-specific cytotoxic T-cell clones are described and characterized. One is K b restricted, the others D b restricted. The factors governing K b or D b restriction patterns seen in the mixed populations from which clones are derived are investigated. Th