✦ LIBER ✦

Critical molecular switches involved in BMP-2-induced osteogenic differentiation of mesenchymal cells

✍ Scribed by Hyun-Mo Ryoo; Mi-Hye Lee; Youn-Jeong Kim

Book ID: 116507357
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 239 KB
Volume: 366
Category: Article
ISSN: 0378-1119
DOI: 10.1016/j.gene.2005.10.011

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## Abstract The effects of Osteogenic Protein‐1 (OP‐1, BMP‐7) on the differentiation of the pluripotent mesenchymal cell line, C2C12, were examined. OP‐1 at 50 ng/ml partially inhibited myotube formation in C2C12 cells, while OP‐1 at 200 ng/ml completely inhibited myotube formation and induced the