BMP treatment of C3H10T1/2 mesenchymal s
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Colleen M. Shea; Cory M. Edgar; Thomas A. Einhorn; Louis C. Gerstenfeld
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Article
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2003
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John Wiley and Sons
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English
β 546 KB
The molecular mechanisms by which bone morphogenetic proteins (BMPs) promote skeletal cell differentiation were investigated in the murine mesenchymal stem cell line C3H10T1/2. Both BMP-7 and BMP-2 induced C3H10T1/2 cells to undergo a sequential pattern of chondrogenic followed by osteogenic differe