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Identification and analysis of type II TGF- receptors in BMP-9-induced osteogenic differentiation of C3H10T1/2 mesenchymal stem cells

✍ Scribed by Wu, N.; Zhao, Y.; Yin, Y.; Zhang, Y.; Luo, J.


Book ID
111860924
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
480 KB
Volume
42
Category
Article
ISSN
1672-9145

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The molecular mechanisms by which bone morphogenetic proteins (BMPs) promote skeletal cell differentiation were investigated in the murine mesenchymal stem cell line C3H10T1/2. Both BMP-7 and BMP-2 induced C3H10T1/2 cells to undergo a sequential pattern of chondrogenic followed by osteogenic differe