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Higher BMP receptor expression and BMP-2-induced osteogenic differentiation in tendon-derived stem cells compared with bone-marrow-derived mesenchymal stem cells

✍ Scribed by Yun Feng Rui; Pauline Po Yee Lui; Yuk Wai Lee; Kai Ming Chan


Book ID
113026999
Publisher
Springer
Year
2011
Tongue
English
Weight
797 KB
Volume
36
Category
Article
ISSN
0341-2695

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## Abstract This study aimed to investigate the effect of repetitive tensile loading on the expression of BMP‐2 and the effect of BMP‐2 on the osteogenic differentiation of tendon‐derived stem cells (TDSCs) in vitro. Repetitive stretching was applied to TDSCs isolated from rat patellar tendon at 0%

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## Abstract Bone marrow‐derived mesenchymal stem cells (BMDMSCs) have been targeted for use in enhancement of bone healing; and their osteogenic potential may be further augmented by genes encoding bone morphogenetic proteins (BMP's). The purpose of this study was to compare the effect of genetic m