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CP-101,606: An NR2B-Selective NMDA Receptor Antagonist

✍ Scribed by Frank S. Menniti; Ajit K. Shah; Stephen A. Williams; Keith D. Wilner; W. Frost White; Bertrand L. Chenard


Book ID
109105445
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
218 KB
Volume
4
Category
Article
ISSN
1080-563X

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## Abstract Glutamate antagonists decrease dyskinesia and augment the antiparkinsonian effects of levodopa in animal models of Parkinson's disease (PD). In a randomized, double‐blind, placebo‐controlled clinical trial, we investigated the acute effects of placebo and two doses of a NR2B subunit sel