Effects of a NR2B selective NMDA glutama
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John G. Nutt; Steven A. Gunzler; Trish Kirchhoff; Penelope Hogarth; Jerry L. Wea
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Article
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2008
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John Wiley and Sons
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English
β 175 KB
## Abstract Glutamate antagonists decrease dyskinesia and augment the antiparkinsonian effects of levodopa in animal models of Parkinson's disease (PD). In a randomized, doubleβblind, placeboβcontrolled clinical trial, we investigated the acute effects of placebo and two doses of a NR2B subunit sel