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Correspondent reaction of mitotic recombination in yeast and sister chromatid exchange in human lymphocytes

✍ Scribed by Fahrig, Rudolf


Publisher
Springer
Year
1981
Tongue
English
Weight
234 KB
Volume
181
Category
Article
ISSN
0026-8925

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This study examined the effect of pyrimethamine (PYR) on sister chromatid exchanges (SCEs) in human lymphocytes. PYR is a folic acid antagonist used for the treatment of malaria and toxoplasmosis. PYR was added to peripheral blood lymphocyte cultures at three different doses: 0.05, 0.1, and 0.2 mg/m