Copper-promoted CN bond cross-coupling with phenylstannane
✍ Scribed by Patrick Y.S. Lam; Guillaume Vincent; Damien Bonne; Charles G. Clark
- Book ID
- 104250780
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 74 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Acyclic and cyclic esters, as well as anhydride (boroxine) of phenylboronic acids are efficient phenylating agents in copper promoted C N and C O bond cross-coupling reactions. The first successful C N cross-coupling of a heterocyclic boronate with heteroarenes, such as indazole, has been demonstrat
The mildest method of N-vinylation has been discovered. The synthetic utilities of the N-and O-vinylated products include protecting group, cyclopropanation and Grubbs' ring closure metathesis reactions.
General catalytic Cu(OAc) 2 /TEMPO in air or Cu(OAc) 2 /O 2 systems for the C N and C O cross-coupling reactions with arylboronic acid have been discovered. N-and O-vinylation have also been demonstrated.