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Copper-catalyzed reaction of aryl iodides with active methylene compounds

✍ Scribed by Okuro, Kazumi; Furuune, Makoto; Miura, Masahiro; Nomura, Masakatsu


Book ID
120071029
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
247 KB
Volume
58
Category
Article
ISSN
0022-3263

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Efficient Copper-Catalyzed Cross-Couplin
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## Abstract A copper‐catalyzed cross‐coupling reaction of alkynes with aryl iodides is described. The system tolerates a broad range of functional groups and enables the use of sterically demanding substrates with only 1.0–2.5 mol‐% of Cu~2~O and 1.0–2.5 mol‐% of xantphos as the catalyst.