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CuI/L-Proline-Catalyzed Coupling Reactions of Aryl Halides with Activated Methylene Compounds.

โœ Scribed by Xiaoan Xie; Guorong Cai; Dawei Ma

Publisher
John Wiley and Sons
Year
2006
Weight
32 KB
Volume
37
Category
Article
ISSN
0931-7597

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CuI-catalyzed Coupling Reactions of Aryl
CuI-catalyzed Coupling Reactions of Aryl Iodides with Amides Using L-Proline and KF/Al2O3
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An efficient experimentally simple and inexpensive catalyst system for the selective amidation of aryl iodides using 15 mol% of CuI as catalyst, 15 mol% of L-proline as ligand and KF/Al 2 O 3 as a base in toluene is described.