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Efficient Copper-Catalyzed Cross-Coupling Reaction of Alkynes with Aryl Iodides

✍ Scribed by Che-Hung Lin; Yu-Jen Wang; Chin-Fa Lee


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
110 KB
Volume
2010
Category
Article
ISSN
1434-193X

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✦ Synopsis


Abstract

A copper‐catalyzed cross‐coupling reaction of alkynes with aryl iodides is described. The system tolerates a broad range of functional groups and enables the use of sterically demanding substrates with only 1.0–2.5 mol‐% of Cu~2~O and 1.0–2.5 mol‐% of xantphos as the catalyst.


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