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An Efficient Copper-Catalyzed Cross-Coupling Reaction of Thiols with Aryl Iodides

✍ Scribed by Hsin-Lun Kao; Chin-Keng Chen; Yu-Jen Wang; Chin-Fa Lee


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
347 KB
Volume
2011
Category
Article
ISSN
1434-193X

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## Abstract A copper‐catalyzed cross‐coupling reaction of alkynes with aryl iodides is described. The system tolerates a broad range of functional groups and enables the use of sterically demanding substrates with only 1.0–2.5 mol‐% of Cu~2~O and 1.0–2.5 mol‐% of xantphos as the catalyst.

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