Conversion of L-Cysteine into D-α-Amino Acids and Related Transformations
✍ Scribed by Rudolf O. Duthaler; Bernhard Wyss
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 736 KB
- Volume
- 2011
- Category
- Article
- ISSN
- 1434-193X
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📜 SIMILAR VOLUMES
The nucleophilic ring opening of gem-dicyanoepoxides by LiBr or Li 2 NiBr 4 , in the presence of hydroxylamine derivatives leads to new α-halo hydroxamic acids. These compounds has been used in the synthesis of αfunctionalized hydroxamic acids, α-hydroxy and α-amino acids in good yields.
## Abstract A synthesis of α,β‐dehydroamino acid derivatives **12** is described, which is of possible general applicability and might be useful for the preparation of peptides which have such a moiety in their sequence. In addition, several didehydrodioxopiperazines (**13–17**) have been prepared.