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Stereocontrolled conversion of L-serine into a series of valuable unnatural α-amino acids

✍ Scribed by Ari M.P. Koskinen; Heikki Hassilla; Vesa T. Myllymäki; Kari Rissanen

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
179 KB
Volume
36
Category
Article
ISSN
0040-4039

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A novel biocatalytic process for production of l-homoalanine from l-threonine has been developed using coupled enzyme reactions consisting of a threonine deaminase (TD) and an w-transaminase (w-TA). TD catalyzes the dehydration/deamination of l-threonine, leading to the generation of 2-oxobutyrate w