Convenient Method for the Kinetic Resolution of β-Amino Alcohols.
✍ Scribed by Beatrice Pelotier; Ghislaine Priem; Simon J. F. Macdonald; Mike S. Anson; Richard J. Upton; Ian B. Campbell
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 32 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract We describe a simple and efficient enzymatic tandem reaction for the preparation of enantiomerically pure __β__‐phenylalanine and its analogues from the corresponding racemates. In this process, phenylalanine aminomutase (PAM) catalyzes the stereoselective isomerization of (__R__)‐__β__
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
Chemoenzymatic dynamic kinetic resolution of b-hydroxy nitriles 1 has been carried out using Candida antarctica lipase B and a ruthenium catalyst. The use of a hydrogen source to depress ketone formation in the dynamic kinetic resolution yields the corresponding acetates 2 in good yield and high ena