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Control of Tyrosine Aminotransferase Synthesis in Tissue Culture by a Factor in Serum

✍ Scribed by Thomas D. Gelehrter and Gordon M. Tomkins

Book ID
123649445
Publisher
National Academy of Sciences
Year
1969
Tongue
English
Weight
374 KB
Volume
64
Category
Article
ISSN
0027-8424

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Control of phenylalanine hydroxylase syn
Control of phenylalanine hydroxylase synthesis in tissue culture by serum and insulin
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## Abstract Stationary‐phase, minimal deviation hepatoma H4‐II‐E‐C3 cell cultures that are serum‐deprived respond with a biphasic time course of phenyl‐alanine hydroxylase induction when dialyzed fetal calf serum or insulin is added. These two agents induce phenylalanine hydroxylase additively, dur