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Continuous cultivation of hybridoma cells in cell reactor

✍ Scribed by Vyacheslav P. Pankratov; Yuri A. Mantzygin; Oleg S. Morenkov; Natal'ya V. Swyatukhina

Publisher
Springer Netherlands
Year
1985
Tongue
English
Weight
332 KB
Volume
7
Category
Article
ISSN
0141-5492

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## Abstract **BACKGROUND:** The production of Monoclonal antibodies (mAbs) is often performed in batch or fed‐batch operations where low cell densities and low volumetric productivities are achieved. The main bottleneck of both processes is the short operating time with productive cells at maximum