Constitutional and somatic deletions of two different regions of maternal chromosome 11 in Wilms tumor
β Scribed by Jeanpierre, C.; Antignac, C.; Beroud, C.; Lavedan, C.; Henry, I.; Saunders, G.; Williams, B.; Glaser, T.; Junien, C.
- Book ID
- 123536018
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 591 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0888-7543
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract BeckwithβWiedemann syndrome (BWS) is a congenital overgrowth disorder with a varying spectrum of clinical manifestations including macroglossia, omphalocele, hemihypertrophy, and a predisposition to a subset of embryonal tumors, most frequently Wilms' tumor (WT). A variety of cytogeneti
## Incidence rates of Wilms' tumor (WT) markedly differ in East Asian and Caucasian children. In the present study, we examined WT1 deletions/mutations and loss of heterozygosity (LOH) on 11p and 11q in a large number of WTs and compared our findings with those from 4 series of Caucasian WTs. Inci
We have studied the involvement of chromosomal bands I I p I 3 and I I p 15.5 in I 5 testicular seminomas (SE) and I8 testicular nonseminomatous germ cell tumors (NS). NO allelic imbalances were found in 40% of the SE and 44% of the NS. LOSS of heterozygosity (LOH) at I I p 15.5 was seen in 2 I % of