## Incidence rates of Wilms' tumor (WT) markedly differ in East Asian and Caucasian children. In the present study, we examined WT1 deletions/mutations and loss of heterozygosity (LOH) on 11p and 11q in a large number of WTs and compared our findings with those from 4 series of Caucasian WTs. Inci
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Deletion ofWT1andWIT1Genes and Loss of Heterozygosity on Chromosome 11p in Wilms Tumors in Japan
โ Scribed by Kaneko, Yasuhiko ;Takeda, Osamu ;Homma, Chieko ;Maseki, Nobuo ;Miyoshi, Hiroyuki ;Tsunematsu, Yukiko ;Williams, Bryan G. ;Saunders, Grady F. ;Sakurai, Masaharu
- Book ID
- 108579661
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1993
- Tongue
- English
- Weight
- 565 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0910-5050
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Wilms tumor (WT) is a kidney malignancy of childhood characterized by highly heterogeneous genetic alterations. We previously reported the molecular and cytogenetic characterization of a WT (Case 30) carrying an interstitial deletion in chromosome 7p14 between markers D7S555 and D7S668. Loss of hete