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Loss of heterozygosity at 11p13 in Wilms' tumours does not necessarily involve mutations in the WT1 gene

✍ Scribed by Cowell, JK; Groves, N; Baird, P


Book ID
109836872
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
727 KB
Volume
67
Category
Article
ISSN
0007-0920

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Mutations/deletions of the WT1 gene, los
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## Incidence rates of Wilms' tumor (WT) markedly differ in East Asian and Caucasian children. In the present study, we examined WT1 deletions/mutations and loss of heterozygosity (LOH) on 11p and 11q in a large number of WTs and compared our findings with those from 4 series of Caucasian WTs. Inci