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Conservation of miR-15a/16-1 and miR-15b/16-2 clusters

✍ Scribed by Junming Yue; Gabor Tigyi

Book ID
106015569
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
479 KB
Volume
21
Category
Article
ISSN
0938-8990

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## Abstract Micro RNAs (miRs) are small noncoding RNAs, functioning as antisense regulators of other RNAs. __miR‐15a__ and __miR‐16‐1__ genes are located at chromosome 13q14, a region which is frequently deleted in pituitary tumors. An inverse correlation has been shown in B cell chronic lymphocyti