miR-15a/16-1 influencesBCL2expression in keratocystic odontogenic tumors
✍ Scribed by Marina Gonçalves Diniz, Carolina Cavaliéri Gomes, Wagner Henriques de Castro, André Luiz Sena Guimarães, Alfredo Maurício Batista De Paula, Hope Amm, Chanchung Ren, Mary MacDougall, Ricardo Santiago Gomez
- Book ID
- 118303794
- Publisher
- Springer Netherlands
- Year
- 2012
- Tongue
- English
- Weight
- 348 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1570-5870
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## Abstract Micro RNAs (miRs) are small noncoding RNAs, functioning as antisense regulators of other RNAs. __miR‐15a__ and __miR‐16‐1__ genes are located at chromosome 13q14, a region which is frequently deleted in pituitary tumors. An inverse correlation has been shown in B cell chronic lymphocyti
## Abstract MicroRNAs (miRNAs) are small, non‐coding RNAs that negatively regulate the expression of protein coding genes. In this study, we screened highly informative prostate cancer cell lines and xenografts (__n__ = 42) for miRNA gene copy number and expression changes. The expression profiling