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Conservation and divergence of Grb7 family of Ras-binding domains

โœ Scribed by Raju V. S. Rajala; Ammaji Rajala; Vivek K. Gupta

Book ID
107692186
Publisher
SP Higher Education Press
Year
2012
Tongue
English
Weight
754 KB
Volume
3
Category
Article
ISSN
1674-800X

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## Abstract Grb7 is a member of the Grb7 family of proteins, which also includes Grb10 and Grb14. All three proteins have been found to be overexpressed in certain cancers and cancer cell lines. In particular, Grb7 (along with the receptor tyrosine kinase erbB2) is overexpressed in 20โ€“30% of breast