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Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14

โœ Scribed by Depetris, Rafael S; Wu, Jinhua; Hubbard, Stevan R


Book ID
109965708
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
794 KB
Volume
16
Category
Article
ISSN
1545-9993

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The growth factor receptor-bound protein-2 (Grb2) is an adaptor protein that mediates signal transduction pathways. Chemical shift assignments were obtained for the SH2 domain of Grb2 by heteronuclear NMR spectroscopy, employing the uniformly 13C-/15N-enriched protein as well as the protein containi