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Conformational studies of 5-acetyl-10-cyano-10,11-dihydro-5H-dibenz[b,f]azepine

โœ Scribed by C.R. Ellefson; L. Swenton; R.H. Bible Jr.; P.M. Green


Publisher
Elsevier Science
Year
1976
Tongue
French
Weight
480 KB
Volume
32
Category
Article
ISSN
0040-4020

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The stereoselectivity of the reduction of 5-carbamoyl-l0, I 1-dihydro-1 l-oxo-SH-dibenz[bflazepine-lO-yl acetate (6), prepared in two steps from 10, I l-dihydro-lO-oxo-5H-dibenz[hflazepine-5-carboxamide (4), has been studied. Among the reagents used, diisobutylaluminum hydride (DIBAH) was found to g