The title compounds were prepared by condensation of a suitably protected monosaccharide and (RI-or W2chloropropanoic acid. Characterization by 'H and 13C NMR spectroscopy revealed minor chemical shift differences between the diastereomers. CD spectra showed differences between the (RIand (S)-l-carb
Conformational analysis of methyl 6-O-[(R)- and (S)-1-carboxyethyl]-α-D-galactopyranoside by MM and Langevin dynamics simulations
✍ Scribed by Roland Stenutz; Goran Widmalm
- Book ID
- 110372218
- Publisher
- Springer US
- Year
- 1997
- Tongue
- English
- Weight
- 952 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1573-4986
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📜 SIMILAR VOLUMES
Conformational analysis of a-D-Manp-(1 ~ 6)-a-D-Manpl-OMe, by a combination of extensive molecular dynamics calculations in water and ROE buildup series, afforded two main minima, namely, ~b/~/, = 95/-178 and q~/~b = 140/-185. Transitions between these minima are observed, which have not previously
X-ray crystallographic analyses are reported for the two title compounds (8 and 9), of which the former crystallized in two modifications (8n and 8b). In all three structures, the pyranose rings have the %, (D) conformation and the substituents at C-l are axial and those at C-24-4 are equatorial. Th