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Concise Stereoselective Total Synthesis of (4 R , 6 R )-Lactone Moiety Analog of Mevinoline and Compactin

✍ Scribed by Rao, D. Chandra; Reddy, D. Kumar; Chinnababu, B.; Shekhar, V.; Venkateswarlu, Y.


Book ID
120660527
Publisher
Taylor and Francis Group
Year
2013
Tongue
English
Weight
180 KB
Volume
43
Category
Article
ISSN
0039-7911

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Enantioselective synthesis of the lacton
✍ Toshio Honda; Satoko Ono; Hirotake Mizutani; Keith O. Hallinan πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 217 KB

The enantioselective synthesis of the lactone moiety of (+)-compactin and (+)mevinolin was established starting from a meso-3,5-dihydroxycyclohexanone derivative by employing an enantioselective deprotonation strategy. (~