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Enantioselective synthesis of (+)-(S)-7,8-dihydrokavain and (4R,6R)-4-hydroxy-6-(2-phenylethyl)tetrahydro-2H-pyran-2-one, lactone analog of compactin and mevinolin

โœ Scribed by I. V. Mineeva


Book ID
120771879
Publisher
SP MAIK Nauka/Interperiodica
Year
2013
Tongue
English
Weight
238 KB
Volume
49
Category
Article
ISSN
1070-4280

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Enantioselective synthesis of the lacton
โœ Toshio Honda; Satoko Ono; Hirotake Mizutani; Keith O. Hallinan ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 217 KB

The enantioselective synthesis of the lactone moiety of (+)-compactin and (+)mevinolin was established starting from a meso-3,5-dihydroxycyclohexanone derivative by employing an enantioselective deprotonation strategy. (~