Computational approach for designing thermostable Candida antarctica lipase B by molecular dynamics simulation
✍ Scribed by Park, Hyun June; Park, Kyungmoon; Kim, Yong Hwan; Yoo, Young Je
- Book ID
- 126614880
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 557 KB
- Volume
- 192
- Category
- Article
- ISSN
- 0168-1656
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## Abstract Candida antarctica __lipase B catalyzed the stereoselective ammoniolysis of__ N__‐alkyl aziridine‐2‐carboxylates in__ t__BuOH saturated with ammonia and yielded the (2__S__)‐aziridine‐2‐carboxamide and unreacted (2__R__)‐aziridine‐2‐carboxylate. Varying the N‐1 substituent on the azirid
The inside cover picture shows that the wrong hand can fit into a glove in two different ways. Recognizing the incorrect fit requires different mechanisms: 1) fingers mismatched or 2) palm curl incorrect. Similarly, the wrong enantiomer can fit into an enzyme's active site in different ways and requ