𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Molecular Basis for the Enantioselective Ring Opening of β-Lactams Catalyzed by Candida antarctica Lipase B

✍ Scribed by Seongsoon Park; Enikö Forró; Harjap Grewal; Ferenc Fülöp; Romas J. Kazlauskas

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
198 KB
Volume
345
Category
Article
ISSN
1615-4150

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Molecular Basis for the Stereoselective
Molecular Basis for the Stereoselective Ammoniolysis of N-Alkyl Aziridine-2-Carboxylates Catalyzed by Candida antarctica Lipase B
✍ Jae-Hoon Park; Hyun-Joon Ha; Won Koo Lee; Tobie Généreux-Vincent; Romas J. Kazla 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 480 KB 👁 1 views

## Abstract Candida antarctica __lipase B catalyzed the stereoselective ammoniolysis of__ N__‐alkyl aziridine‐2‐carboxylates in__ t__BuOH saturated with ammonia and yielded the (2__S__)‐aziridine‐2‐carboxamide and unreacted (2__R__)‐aziridine‐2‐carboxylate. Varying the N‐1 substituent on the azirid

Inside Cover: Molecular Basis for the St
Inside Cover: Molecular Basis for the Stereoselective Ammoniolysis of N-Alkyl Aziridine-2-Carboxylates Catalyzed by Candida antarctica Lipase B (ChemBioChem 13/2009)
✍ Jae-Hoon Park; Hyun-Joon Ha; Won Koo Lee; Tobie Généreux-Vincent; Romas J. Kazla 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB 👁 1 views

The inside cover picture shows that the wrong hand can fit into a glove in two different ways. Recognizing the incorrect fit requires different mechanisms: 1) fingers mismatched or 2) palm curl incorrect. Similarly, the wrong enantiomer can fit into an enzyme's active site in different ways and requ

An Inverse Substrate Orientation for the
An Inverse Substrate Orientation for the Regioselective Acylation of 3′,5′-Diaminonucleosides Catalyzed by Candida antarctica lipase B?
✍ Iván Lavandera; Susana Fernández; Julia Magdalena; Miguel Ferrero; Romas J. Kazl 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 243 KB 👁 1 views

## Abstract Candida antarctica __lipase B (CAL‐B) catalyzes the regioselective acylation of natural thymidine with oxime esters and also the regioselective acylation of an analogue, 3′,5′‐diamino‐3′,5′‐dideoxythymidine with nonactivated esters. In both cases, acylation favors the less hindered 5′‐p